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Ultrafiltration (UF) is a pressure-driven barrier to suspended solids, bacteria, viruses, endotoxins and other pathogens to produce water with very high purity and low silt density. Ultrafiltration (UF) is a variety of membrane filtration in which hydrostatic pressure forces a liquid against a semi permeable membrane.

Ultrafiltration removes excess plasma volume without causing a significant change in electrolytes. In patients with chronic heart failure and diuretic resistance, ultrafiltration improves symptoms, neurohormones, and hemodynamics without hypotension